Get your dander up

Meaning

To become angry, agitated, or ready to fight. Dander refers to dandruff or tiny particles, suggesting the person is bristling like an animal getting ready for a confrontation.

Warny, colorful

Used in a sentence

• I would not bring up the politics of the club if I were you, it really gets his dander up.
• She rarely gets her dander up, but that rude comment really set her off.
• The barking dog got the cat's dander up pretty quickly.